Pradaxa Recall: It’s called a thrombosis, the most common form of stroke. In fact, 80-85 percent of all strokes are ischemic in nature. Here, the blood flow in the brain, either deep in its interior or in the less deep carotid artery in the neck, is blocked because of a clot that forms in the artery. Atherosclerosis is its greatest influence. Think of it. Either through cholesterol deposits or aging, the in”side walls of the arteries become less flexible; thick deposits of fat form, and passageways become too narrow for blood to flow through smoothly. Instead, the blood forms a clot around these thick deposits as it tries to get past. Unfortunately, this decline has plateaued recently, which further shows that other risk factors must be treated as well. A lower-fat diet that is also lower in salt, exercise, weight loss, no smoking, even taking one drink of alcohol a day (but don’t forget that heavy drinking increases the risk of stroke!)—all these can help reduce the risk of stroke. And reducing one risk factor can have a favorable outcome on the others. As we have seen, many conditions are related: high cholesterol and hypertension, obesity and diabetes. Treating one of these factors can help treat another.
Ironically, these clots usually begin as a healthy measure. The deposits or rough places on the artery wall are seen by the body as a “call to arms,” a need to stave off infection. The blood, thinking these areas need repair, clots around them. Platelets send out their thin clotting fibers. Red and white blood cells join in the action. Soon, the clotting has a life of its own, acting like a net as it pulls platelets, red blood cells, even bits of floating cholesterol into its web. A scab can form, making the mass of cholesterol and blood even thicker.
This type of stroke, too, is caused by a clot. These embolic strokes are less common than their thrombotic cousin. But these clots, called emboli, are the traveling salespeople of stroke, a mass of tissue, blood, and cholesterol that originates somewhere else in our body, usually in the heart or the neck’s carotid artery, only to end up in the brain. Here, when the clotting action occurs, a piece of clot eventually breaks off. This clot, or embolism, is carried by the bloodstream to the brain, where the arteries are smaller. Soon, the clot gets stuck, literally plugging up the passageway beyond it. Blood simply cannot get past the embolism.
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Pradaxa Recall